I think it's good, but you might want to work on the size of the hand a little bit in the final version. Keep in mind your hand is usually the length of your face. :)
your hand drawn work is more compelling than the vectorized tie and folds in the shirt - they have good form, but I'd like to see them in a similar style as the girl. I love the eye.
freaky idea, though I'm not diggin' the shape of the creeps fingers, they don't look right. It's like they are too bent. I love the expression on his face though.